yeast knockout collection is a collection of ~4700 (S. cerevisiae) strains, each of them engineered to contain a precise deletion of a single non-essential gene.
Four different knockout collections exist:
Haploid, of mating type "a"
Haploid, of mating type "alpha"
Diploid, heterozygous knockout
Haploid, homozygous knockout
We have sequenced the whole genome of the large majority of strains in the homozygous
diploid knockout collection and generated a “genome-instability profile” for each of them.